Fear, Sleep, Stress, PTSS and our Poor Inattentive ADHD Rat

Inattentive ADHD and PTSS
There is a little fearful, stressed out, sleep deprived, inattentive rat that is a rat model for Inattentive ADHD.  It turns out that this same rat may be a good model for Post Traumatic Stress Syndrome (PTSS) as well.  The name of our little rat cousin is the Charles River Wistor-Kyoto or (WKY) rat.

I found this study about PTSS because, (you may think this strange), every once in a while, just for jollies, I check the literature to see what they have been doing to this poor rat and I try to understand how it applies to us. (You are absolutely right!  I need to get a life).

You may be interested to know that they have been scaring this poor rat, out of its wits, and have discovered some interesting things about sleep and stress. It turns out that, not too surprisingly, our little rat friend is extremely sensitive to stress.

The researchers of this study knew that the WKY rat was hypersensitive to stress but that is not what they wanted to know about the rat. What they wanted to know was how that stress reaction affected the rats sleep.

What they found was that when this rat experienced significant stress, the REM sleep of the rat remained disturbed and the researchers thought that our very own WKY rat would make a great model for Post Traumatic Stress Syndrome. The authors reported that the "WKY rat may be a good model for investigating the neurobiological mechanisms of sleep disturbances reported in posttraumatic stress disorder."

I would take from this that people with Post Traumatic Stress Syndrome can have some similar features to people with Inattentive ADHD. This is not at all surprising to me. I must look at my list of  171 diagnoses that look like ADHD but are not, and make sure that PTSS is among those listed. (Just looked, it's there #128).

Progress in Neuropsychopharmacology and Biological Psychiatry. 2011 Jan
Fear conditioning fragments REM sleep in stress-sensitive Wistar-Kyoto, but not Wistar, rats.
DaSilva JK, Lei Y, Madan V, Mann GL, Ross RJ, Tejani-Butt S, Morrison AR.

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